DIGESTIVE SYSTEM

DIGESTIVE SYSTEM  [1]

ULCERS:

The beneficial effect of ginger against ulcer is more important as preventive treatment than a treatment. Can be caused by its antibacterial effect on Helicobacter pylori, bacteria associated with many forms of gastroduodenal ulcer.

Gastric ulcers, or stomach ulcers, develop in the lining of the stomach. They are very common, affecting between 2.4–6.1% of the population. Various factors that disrupt the balance your stomach’s environment can cause them. The most common is an infection caused by the Helicobacter pylori bacteria [2]

DIARRHEA: [1]

Ginger has some antibacterial activity but unaffected Lactobacillus.
Consumption of ginger when you have diarrhea helps restore intestinal flora, especially if they are of bacterial origin.

GASTROINTESTINAL(GI) CANCER[3]

Gastrointestinal (GI) cancer, a cancer of different organs of the digestive system, is one of the most common cancers around the world. The incidence and death rate of some of these cancers are very high. Although a large variety of chemotherapeutic agents have been introduced since the last few decades to combat GI cancer, most of them are very expensive and have side effects. Therefore, the compounds derived from natural sources, which are considered to be safe and cost effective, are needed. Ginger (Zingiber officinale) is one of the most widely used natural products consumed as a spice and medicine for treating nausea, dysentery, heartburn, flatulence, diarrhea, loss of appetite, infections, cough, and bronchitis. Experimental studies showed that ginger and its active components including 6-gingerol and 6-shogaol exert anticancer activities against GI cancer.

GASTRIC EMPTYING AND DYSPEPSIA

Ginger as an important dietary agent which possesses carminative effect, decreases pressure on lower esophageal sphincter, reduces intestinal cramping, and prevents dyspepsia, flatulence, and bloating. [1]

FATTY LIVER

Nonalcoholic fatty liver disease (NAFLD) is one of chronic liver diseases throughout the world that mostly is seen in obese, low active people, and patients with type II diabetes

Previous studies have shown that a diet rich in antioxidants and anti‐inflammatory agents can be effective in the treatment of NAFLD (Eslamparast, Eghtesad, Poustchi, & Hekmatdoost, 2015). Rahimlou, Yari, Hekmatdoost, Alavian, & Keshavarz (2016) conducted the first randomized, double‐blind clinical trial study that examined the effects of ginger supplementation with lifestyle intervention on liver enzymes, inflammatory markers, steatosis, and hepatic fibrosis scores in patients with nonalcoholic fatty liver disease (NAFLD). [1]

IRRITABLE BOWEL SYNDROME (IBS)

Irritable bowel syndrome (IBS) is a common functional chronic gastrointestinal disorder, consisting of abdominal discomfort with changes in bowel habits. The effectiveness of current therapeutic strategies for IBS is limited and about 40% of patients use alternative medicine to treat their symptoms (Van Tilburg et al., 2008). Due to the known gastrointestinal effects of ginger, it was reported as the most popular remedy consumed. [1]

DYSPHAGIA

Dysphagia is a major alarm sign in gastroenterology; however, impaired swallowing function from a combination of underlying disease and reduced physical and cognitive abilities could be a result of elderly. [4]

 

 

Notes:

[1] Ginger in gastrointestinal disorders: A systematic review of clinical trials. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341159/
[2] Ginger (Zingiber officinale Roscoe) and the Gingerols Inhibit the Growth of Cag A+ Strains of Helicobacter pylori. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761965/
[3] Ginger and Its Constituents: Role in Prevention and Treatment of Gastrointestinal Cancer.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369959/
[4] Effect of ginger on gastric motility and symptoms of functional dyspepsia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016669/