Ginsix © Forte is a compound belonging to the family of other antiemetics. Its formulation is based on ginger root, to relieve the inconvenient produced by the Anticipatory Chemotherapy Induced Nausea and Vomiting.
Anticipatory Chemotherapy Induced Nausea and Vomiting
Anticipatory CINVs are generally considered to be a conditional response to a previous episode of CINV. A sensory stimulus (e.g., sight, hearing, smell) present at the time of an CINV episode conditions the patient to associate the stimulus with nausea and vomiting.
Post-stimulus exposure triggers the conditioned response of nausea and vomiting. Prevention of acute and delayed CINVs is the best approach for anticipatory CINVs so that a sensory stimulus is not established.
Antiemetics, including the new 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists, do not appear to control ANV and usually are managed with a variety of behavioural interventions as Progressive muscle relaxation with guided imagery, Hypnosis, Systematic desensitization, Electromyography and thermal biofeedback, Distraction via the use of video games… or using natural remedies like ginger.
The active components of ginger Shogaols, gingerols and zingerone present in ginger may contribute to its therapeutic effect.
The active components of ginger inhibit the ion channel of the serotonin receptor by binding to a modulatory site, unlike 5-HT3 receptor antagonists such as ondansetron, which competitively inhibit the receptor at the serotonin recognition site.
Hence ginsix © Forte can be the most effective solution in ANV treatment as provide the suppression of 5-HT receptors eliminating or reducing the reflex of nausea and vomiting and has an important psychological effect for the patient who can avoid assist to costly in time and money therapeutic sessions
4 capsules a day, starting five days prior to the first chemotherapy session and continue during all the treatment.
Ginger Root extract (5% gingerols) 300mg
Vitamin B6 (82.27%) 7,29 mg